In Q3 2025, RTW Investments held 68 positions worth $7.8B. They initiated 7 new positions and exited 51. Their largest holding was MDGL ($914.4M). Portfolio value grew +17.9% versus the prior quarter.
Frequently asked questions
What stocks did RTW Investments own in Q3 2025?
RTW Investments held 68 biotech stocks in their 13F portfolio in Q3 2025. Their top positions include MDGL, ARGX, RNA, PTCT, INSM. The full holdings table is available on BiotechEdge with position sizes, quarter-over-quarter changes, and AI analysis.
How much was RTW Investments's portfolio worth in Q3 2025?
RTW Investments's tracked biotech portfolio was worth $7.8B across 68 positions, with total assets under management of approximately $10B. Portfolio values are based on 13F filings with the SEC.
What did RTW Investments buy in Q3 2025?
RTW Investments initiated 7 new positions in Q3 2025, including COGT, AQST, AAVXF, BLTE, ALEC and 2 more. They also increased 18 existing positions.
What did RTW Investments sell in Q3 2025?
RTW Investments fully exited 51 positions in Q3 2025, including MLTX, SLNO, VRNA, RLMD, VKTX and 46 more. They also trimmed 10 existing positions.
Is RTW Investments a biotech fund?
Data-driven biotech fund led by a physician-investor who combines clinical expertise with quantitative analysis. RTW takes concentrated positions across the biotech lifecycle, from crossover privates to public equities, with a focus on therapeutic areas where clinical data can be independently modeled.
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