Biotech Stocks Set Up for a Short Squeeze
Biotech stocks where short sellers are most exposed. Filtered for high days-to-cover and elevated short interest, then ranked by how many bullish signals stack up — fund buying, approaching catalysts, and more.
Tracking 245 biotech tickers · FINRA data as of Apr 30, 2026 · Updated twice monthly
Short squeeze alerts before they unwind
High DTC, rising SI, fund buying signals — free Monday brief.
How short squeeze scores work
What is a short squeeze?
A short squeeze occurs when a heavily shorted stock rises in price, forcing short sellers to buy shares to cover their positions, which drives the price even higher. Biotech stocks are especially prone to squeezes around binary catalyst events like FDA decisions.
How is the squeeze score calculated?
The squeeze score combines days-to-cover (how long it would take short sellers to exit), short interest as a percentage of float, whether specialist funds are buying, and proximity to upcoming catalysts. Higher scores indicate more squeeze pressure.
What does days-to-cover mean?
Days-to-cover (DTC) is the number of days it would take all short sellers to buy back their shares, based on average daily trading volume. A DTC above 5 means it would take short sellers nearly a week to exit — creating significant squeeze risk if the stock moves up.
How often is short interest data updated?
Short interest data is reported by FINRA twice per month (mid-month and end-of-month settlement dates). We ingest new data as soon as it's published, typically within 24 hours of the settlement date.
Drill into any signal
Fund Convergence
See which stocks multiple specialist funds are buying at once
Catalyst Calendar
Every PDUFA date, Phase 3 readout, and AdCom in one view
Insider Trading
When executives buy their own stock — the strongest bullish signal
Cash Runway
Which biotechs are running low on cash and face dilution risk
Signal Rankings
Every signal in one composite score — ranked by conviction
Biotech Movers
Stocks with the most signal activity right now across all signals
13F Changes
What top biotech funds bought and sold in the latest 13F filing
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