Avoro Capital Advisors RNA Position
Active15-Fund ConvergenceAvoro Capital Advisors trimmed their position in Avidity Biosciences Inc. (RNA) in Q4 2025, holding $393.5M worth of shares across 5,455,000 shares.
The position was first reported in Q1 2023 and has been tracked across 12 quarterly 13F filings.
RNA is a convergence signal: 15 specialist biotech funds hold this stock, suggesting high institutional conviction.
There is an upcoming Phase 3 readout for AOC 1001 (del-desiran) in 137 days (Aug 31, 2026), making the timing of Avoro Capital's position particularly relevant.
About Avidity Biosciences Inc.
Atrium Therapeutics, Inc., a biopharmaceutical company, focuses on delivering ribonucleic acid (RNA) therapeutics to the heart to transform the care for people living with cardiomyopathies. The company's development stage product candidates include ATR 1072, a siRNA-based therapy targeting PRKAG2 for the treatment of PRKAG2 syndrome; and ATR 1086, a siRNA-based therapy targeting PLN for the treatment of PLN cardiomyopathy. It also focuses on pipeline to treat a range of genetic and cardiac diseases. The company was incorporated in 2025 and is headquartered in San Diego, California.
Full company profile →Avoro Capital Advisors RNA Position History
| Quarter | Action | Shares | Change | Value |
|---|---|---|---|---|
| Q4 2025 | Decreased | 5,455,000 | -2,190,000 | $393.5M |
| Q3 2025 | Increased | 7,645,000 | +595,000 | $333.1M |
| Q2 2025 | Decreased | 7,050,000 | -575,000 | $200.2M |
| Q1 2025 | Increased | 7,625,000 | +125,000 | $225.1M |
| Q4 2024 | Increased | 7,500,000 | +625,000 | $218.1M |
| Q3 2024 | Increased | 6,875,000 | +370,000 | $315.8M |
| Q2 2024 | Increased | 6,505,000 | +680,000 | $265.7M |
| Q1 2024 | Increased | 5,825,000 | +3,315,000 | $148.7M |
| Q4 2023 | Held | 2,510,000 | — | $22.7M |
| Q3 2023 | Held | 2,510,000 | — | $16.0M |
| Q2 2023 | Held | 2,510,000 | — | $27.8M |
| Q1 2023 | New | 2,510,000 | +2,510,000 | $38.5M |
Frequently Asked Questions
Does Avoro Capital Advisors own RNA?
Yes. As of Q4 2025, Avoro Capital Advisors holds 5,455,000 shares of Avidity Biosciences Inc. (RNA) valued at $393.5M. This data comes from their SEC 13F filing.
How many hedge funds own RNA?
15 specialist biotech hedge funds currently hold RNA, including RA Capital Management, RTW Investments, Casdin Capital and 11 more. When 3 or more specialist funds hold the same stock, BiotechEdge flags it as a convergence signal.
When did Avoro Capital Advisors first buy RNA?
Avoro Capital Advisors's position in RNA was first reported in Q1 2023. 13F filings are reported with a 45-day delay, so the actual purchase may have occurred earlier in the quarter.
Is Avoro Capital Advisors's RNA position increasing or decreasing?
Avoro Capital Advisors trimmed their RNA position in the most recent quarter, reducing by 2,190,000 shares.
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