Avoro Capital Advisors SLNO Position
Active10-Fund ConvergenceAvoro Capital Advisors increased their position in SOLENO THERAPEUTICS INC (SLNO) in Q4 2025, holding $134.3M worth of shares across 2,900,000 shares.
The position was first reported in Q4 2023 and has been tracked across 9 quarterly 13F filings.
SLNO is a convergence signal: 10 specialist biotech funds hold this stock, suggesting high institutional conviction.
There is an upcoming Phase 3 readout for DCCR in 806 days (Jun 30, 2028), making the timing of Avoro Capital's position particularly relevant.
Short interest stands at 20.7% of float with 5.8 days to cover, indicating significant bearish positioning against Avoro Capital's long thesis.
About SOLENO THERAPEUTICS INC
Soleno Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of novel therapeutics for the treatment of rare diseases. Its lead candidate is Diazoxide Choline Controlled-Release, a once-daily oral tablet for the treatment of Prader-Willi Syndrome, which is being evaluated in an ongoing Phase III clinical development program. The company was formerly known as Capnia, Inc. and changed its name to Soleno Therapeutics, Inc. in May 2017. Soleno Therapeutics, Inc. was incorporated in 1999 and is based in Redwood City, California.
Full company profile →Short Interest
20.7%
5.8 days to cover
Avoro Capital Advisors SLNO Position History
| Quarter | Action | Shares | Change | Value |
|---|---|---|---|---|
| Q4 2025 | Increased | 2,900,000 | +322,223 | $134.3M |
| Q3 2025 | Increased | 2,577,777 | +527,777 | $174.3M |
| Q2 2025 | Decreased | 2,050,000 | -475,000 | $171.7M |
| Q1 2025 | Held | 2,525,000 | — | $180.4M |
| Q4 2024 | Increased | 2,525,000 | +344,000 | $113.5M |
| Q3 2024 | Increased | 2,181,000 | +89,334 | $110.1M |
| Q2 2024 | Increased | 2,091,666 | +466,666 | $85.3M |
| Q1 2024 | Increased | 1,625,000 | +840,000 | $69.5M |
| Q4 2023 | New | 785,000 | +785,000 | $31.6M |
Frequently Asked Questions
Does Avoro Capital Advisors own SLNO?
Yes. As of Q4 2025, Avoro Capital Advisors holds 2,900,000 shares of SOLENO THERAPEUTICS INC (SLNO) valued at $134.3M. This data comes from their SEC 13F filing.
How many hedge funds own SLNO?
10 specialist biotech hedge funds currently hold SLNO, including Perceptive Advisors, Commodore Capital, Deep Track Capital and 6 more. When 3 or more specialist funds hold the same stock, BiotechEdge flags it as a convergence signal.
When did Avoro Capital Advisors first buy SLNO?
Avoro Capital Advisors's position in SLNO was first reported in Q4 2023. 13F filings are reported with a 45-day delay, so the actual purchase may have occurred earlier in the quarter.
Is Avoro Capital Advisors's SLNO position increasing or decreasing?
Avoro Capital Advisors increased their SLNO position in the most recent quarter, adding 322,223 shares.
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