Baker Bros. Advisors KNSA Position
Active4-Fund ConvergenceBaker Bros. Advisors increased their position in Kiniksa Pharmaceuticals International, plc (KNSA) in Q4 2025, holding $116.6M worth of shares across 2,826,246 shares.
The position was first reported in Q1 2023 and has been tracked across 12 quarterly 13F filings.
KNSA is a convergence signal: 4 specialist biotech funds hold this stock, suggesting high institutional conviction.
There is an upcoming Phase 3 readout for KPL-387 in 626 days (Dec 31, 2027), making the timing of Baker Bros.'s position particularly relevant.
About Kiniksa Pharmaceuticals International, plc
Kiniksa Pharmaceuticals, Ltd., a biopharmaceutical company, focuses on discovering, acquiring, developing, and commercializing therapeutic medicines for patients suffering from debilitating diseases with significant unmet medical needs worldwide. Its product candidates include ARCALYST, an interleukin-1alpha and interleukin-1beta, for the treatment of recurrent pericarditis, which is an inflammatory cardiovascular disease; Mavrilimumab, a monoclonal antibody inhibitor that completed Phase II clinical trials for the treatment of giant cell arteritis; Vixarelimab, a monoclonal antibody, which is in Phase 2a clinical trial for the treatment of prurigo nodularis, a chronic inflammatory skin condition; and KPL-404, a monoclonal antibody inhibitor of the CD40- CD154 interaction, a T-cell co-stimulatory signal critical for B-cell maturation, immunoglobulin class switching, and type 1 immune response. Kiniksa Pharmaceuticals, Ltd. was incorporated in 2015 and is based in Hamilton, Bermuda.
Full company profile →Short Interest
8.9%
5.3 days to cover
Baker Bros. Advisors KNSA Position History
| Quarter | Action | Shares | Change | Value |
|---|---|---|---|---|
| Q4 2025 | Increased | 2,826,246 | +1,577 | $116.6M |
| Q3 2025 | Held | 2,824,669 | — | $109.7M |
| Q2 2025 | Increased | 2,824,669 | +6,346 | $78.2M |
| Q1 2025 | Held | 2,818,323 | — | $62.6M |
| Q4 2024 | Held | 2,818,323 | — | $55.7M |
| Q3 2024 | Held | 2,818,323 | — | $70.4M |
| Q2 2024 | Increased | 2,818,323 | +8,746 | $52.6M |
| Q1 2024 | Held | 2,809,577 | — | $55.4M |
| Q4 2023 | Held | 2,809,577 | — | $49.3M |
| Q3 2023 | Held | 2,809,577 | — | $48.8M |
| Q2 2023 | Increased | 2,809,577 | +10,000 | $39.6M |
| Q1 2023 | New | 2,799,577 | +2,799,577 | $30.1M |
Frequently Asked Questions
Does Baker Bros. Advisors own KNSA?
Yes. As of Q4 2025, Baker Bros. Advisors holds 2,826,246 shares of Kiniksa Pharmaceuticals International, plc (KNSA) valued at $116.6M. This data comes from their SEC 13F filing.
How many hedge funds own KNSA?
4 specialist biotech hedge funds currently hold KNSA, including Tang Capital Management, Driehaus Capital, OrbiMed Advisors. When 3 or more specialist funds hold the same stock, BiotechEdge flags it as a convergence signal.
When did Baker Bros. Advisors first buy KNSA?
Baker Bros. Advisors's position in KNSA was first reported in Q1 2023. 13F filings are reported with a 45-day delay, so the actual purchase may have occurred earlier in the quarter.
Is Baker Bros. Advisors's KNSA position increasing or decreasing?
Baker Bros. Advisors increased their KNSA position in the most recent quarter, adding 1,577 shares.
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