Baker Bros. Advisors SANA Position
Active4-Fund ConvergenceBaker Bros. Advisors trimmed their position in Sana Biotechnology, Inc. (SANA) in Q4 2025, holding $1.3M worth of shares across 310,483 shares.
The position was first reported in Q1 2023 and has been tracked across 12 quarterly 13F filings.
SANA is a convergence signal: 4 specialist biotech funds hold this stock, suggesting high institutional conviction.
Short interest stands at 38.2% of float with 16.8 days to cover, indicating significant bearish positioning against Baker Bros.'s long thesis.
About Sana Biotechnology, Inc.
Sana Biotechnology, Inc., a biotechnology company, focuses on utilizing engineered cells as medicines. The company develops ex vivo and in vivo cell engineering platforms for various therapeutic areas with unmet treatment needs, including oncology, diabetes, central nervous system disorders, cardiovascular diseases, genetic disorders, and others. Its product candidates include SG295 and SG242 that target CD19+ cancer cells, including non-Hodgkin Lymphoma, chronic lymphocytic leukemia, and acute lymphoblastic leukemia; SG221 and SG239 for the treatment of multiple myeloma; and SG328 for ornithine transcarbamylase deficiency. It also develops SG418 for sickle cell disease and beta-thalassemia; SC291, a CD19 allogeneic T cell therapy; SC255 for multiple myeloma; SC451 for type I diabetes mellitus; and SC379 for secondary progressive multiple sclerosis, Pelizaeus-Merzbacher disease, and Huntington's disease. Sana Biotechnology, Inc. was formerly known as FD Therapeutics, Inc. and changed its name to Sana Biotechnology, Inc. in September 2018. The company was incorporated in 2018 and is headquartered in Seattle, Washington.
Full company profile →Short Interest
38.2%
16.8 days to cover
Baker Bros. Advisors SANA Position History
| Quarter | Action | Shares | Change | Value |
|---|---|---|---|---|
| Q4 2025 | Decreased | 310,483 | -1,720,466 | $1.3M |
| Q3 2025 | Held | 2,030,949 | — | $7.2M |
| Q2 2025 | Held | 2,030,949 | — | $5.5M |
| Q1 2025 | Decreased | 2,030,949 | -350,000 | $3.4M |
| Q4 2024 | Held | 2,380,949 | — | $3.9M |
| Q3 2024 | Held | 2,380,949 | — | $9.9M |
| Q2 2024 | Held | 2,380,949 | — | $13.0M |
| Q1 2024 | Increased | 2,380,949 | +380,949 | $23.8M |
| Q4 2023 | Held | 2,000,000 | — | $8.2M |
| Q3 2023 | Held | 2,000,000 | — | $7.7M |
| Q2 2023 | Held | 2,000,000 | — | $11.9M |
| Q1 2023 | New | 2,000,000 | +2,000,000 | $6.5M |
Frequently Asked Questions
Does Baker Bros. Advisors own SANA?
Yes. As of Q4 2025, Baker Bros. Advisors holds 310,483 shares of Sana Biotechnology, Inc. (SANA) valued at $1.3M. This data comes from their SEC 13F filing.
How many hedge funds own SANA?
4 specialist biotech hedge funds currently hold SANA, including Boxer Capital, Casdin Capital, Deerfield Management. When 3 or more specialist funds hold the same stock, BiotechEdge flags it as a convergence signal.
When did Baker Bros. Advisors first buy SANA?
Baker Bros. Advisors's position in SANA was first reported in Q1 2023. 13F filings are reported with a 45-day delay, so the actual purchase may have occurred earlier in the quarter.
Is Baker Bros. Advisors's SANA position increasing or decreasing?
Baker Bros. Advisors trimmed their SANA position in the most recent quarter, reducing by 1,720,466 shares.
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