Deerfield Management STOK Position
Active8-Fund ConvergenceDeerfield Management initiated a new position in Stoke Therapeutics, Inc. (STOK) in Q4 2025, holding $57.9M worth of shares across 1,823,500 shares.
STOK is a convergence signal: 8 specialist biotech funds hold this stock, suggesting high institutional conviction.
There is an upcoming Phase 3 readout for zorevunersen in 349 days (Mar 31, 2027), making the timing of Deerfield's position particularly relevant.
Short interest stands at 26.9% of float with 16.9 days to cover, indicating significant bearish positioning against Deerfield's long thesis.
About Stoke Therapeutics, Inc.
Stoke Therapeutics, Inc., an early-stage biopharmaceutical company, develops novel antisense oligonucleotide (ASO) medicines to treat the underlying causes of severe genetic diseases in the United States. The company utilizes its proprietary Targeted Augmentation of Nuclear Gene Output to design ASOs to precisely upregulate protein expression. Its lead clinical candidate is STK-001, which is in phase I/IIa clinical trial to treat Dravet syndrome, a severe and progressive genetic epilepsy; and STK-002, which is in preclinical stage for the treatment of autosomal dominant optic atrophy. It had entered into a license and collaboration agreement with Acadia Pharmaceuticals Inc. for the discovery, development, and commercialization of novel RNA-based medicines for the treatment of severe and rare genetic neurodevelopmental diseases of the central nervous system. The company was formerly known as ASOthera Pharmaceuticals, Inc. and changed its name to Stoke Therapeutics, Inc. in May 2016. Stoke Therapeutics, Inc. was incorporated in 2014 and is headquartered in Bedford, Massachusetts.
Full company profile →Short Interest
26.9%
16.9 days to cover
Frequently Asked Questions
Does Deerfield Management own STOK?
Yes. As of Q4 2025, Deerfield Management holds 1,823,500 shares of Stoke Therapeutics, Inc. (STOK) valued at $57.9M. This data comes from their SEC 13F filing.
How many hedge funds own STOK?
8 specialist biotech hedge funds currently hold STOK, including RTW Investments, Redmile Group, Baker Bros. Advisors and 4 more. When 3 or more specialist funds hold the same stock, BiotechEdge flags it as a convergence signal.
When did Deerfield Management first buy STOK?
Deerfield Management's position in STOK was first reported in Q4 2025. 13F filings are reported with a 45-day delay, so the actual purchase may have occurred earlier in the quarter.
Is Deerfield Management's STOK position increasing or decreasing?
Deerfield Management initiated a new position in STOK in the most recent quarter. This is their first reported holding.
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