In Q4 2025, Driehaus Capital held 330 positions worth $12.8B. They initiated 36 new positions and exited 440. Their largest holding was CRNX ($297.3M).
Portfolio Value (13F)
$12.8B
Holdings
330
Top 10 Concentration
15.1%
QoQ Change
N/A
Turnover
3.8%
Sector Breakdown
Biotechnology95%(312)
Other Healthcare5%(18)
Q4 2025 Holdings (330)
| # | Ticker | Company | Change | Value | % of Portfolio | SI % Float ? |
|---|---|---|---|---|---|---|
| 1 | CRNX | Crinetics Pharmaceuticals Inc. | Decreased | $297.3M | 2.33% | 16.5% |
| 2 | PRAX | Praxis Precision Medicines, Inc. | Increased | $275.0M | 2.15% | 13.5% |
| 3 | GH | Guardant Health Inc. | Decreased | $218.9M | 1.72% | 9.1% |
| 4 | XENE | Xenon Pharmaceuticals Inc. | Increased | $203.4M | 1.59% | 6.2% |
| 5 | PLNT | Planet Fitness, Inc. | Decreased | $182.0M | 1.43% | 10.1% |
| 6 | APGE | Apogee Therapeutics Inc. | Increased | $164.8M | 1.29% | 23.2% |
| 7 | EOSE | Eos Energy Enterprises, Inc. | Increased | $163.5M | 1.28% | 28.3% |
| 8 | SITM | Sitime Corp. | Decreased | $145.8M | 1.14% | 7.3% |
| 9 | NTRA | Natera Inc. | Increased | $143.4M | 1.12% | 2.4% |
| 10 | CCJ | Cameco Corp. | Decreased | $139.3M | 1.09% | — |
| 11 | FTAIN | FTAI Aviation Ltd. | Increased | $137.9M | 1.08% | — |
| 12 | RYTM | Rhythm Pharmaceuticals Inc. | Decreased | $137.6M | 1.08% | 12.2% |
| 13 | HDB | Hdfc Bank Ltd. | Increased | $136.0M | 1.07% | 0.2% |
| 14 | BAP | Credicorp Ltd. | Increased | $135.5M | 1.06% | 1.7% |
| 15 | SEPN | Septerna, Inc. | Decreased | $134.1M | 1.05% | 8.0% |
| 16 | BBIO | BridgeBio Pharma Inc. | Increased | $128.6M | 1.01% | 20.2% |
| 17 | PI | Impinj Inc. | Increased | $128.3M | 1.01% | 19.1% |
| 18 | CRS | Carpenter Technology Corp. | Increased | $127.0M | 0.99% | 4.4% |
| 19 | LITE | Lumentum Holdings Inc. | Decreased | $125.7M | 0.98% | 18.0% |
| 20 | IBN | Icici Bank Ltd. | Decreased | $121.1M | 0.95% | 1.6% |
| 21 | IDCC | InterDigital, Inc. | Increased | $119.4M | 0.94% | 15.3% |
| 22 | XMTR | Xometry, Inc. | Increased | $118.1M | 0.93% | 11.3% |
| 23 | ARWR | Arrowhead Pharmaceuticals Inc. | Decreased | $117.5M | 0.92% | 11.4% |
| 24 | NHCOther Healthcare | National Healthcare Corp. | Increased | $116.5M | 0.91% | 5.6% |
| 25 | GPCR | Structure Therapeutics Inc. | Increased | $114.2M | 0.89% | 9.9% |
| 26 | WVE | Wave Life Sciences Ltd. | Increased | $111.9M | 0.88% | 9.1% |
| 27 | FN | Fabrinet | Decreased | $109.7M | 0.86% | 9.4% |
| 28 | WFRD | Weatherford International plc | Increased | $108.3M | 0.85% | 7.8% |
| 29 | UEC | Uranium Energy Corp. | Decreased | $106.4M | 0.83% | 13.2% |
| 30 | EWTX | Edgewise Therapeutics, Inc. | Increased | $104.0M | 0.81% | 10.3% |
| 31 | EMBJ | Embraer S.A. | Increased | $102.3M | 0.80% | 1.0% |
| 32 | KRMN | Karman Holdings Inc. | Decreased | $99.2M | 0.78% | 6.9% |
| 33 | PTGX | Protagonist Therapeutics Inc. | Decreased | $96.0M | 0.75% | 15.1% |
| 34 | TARS | Tarsus Pharmaceuticals Inc. | Increased | $96.0M | 0.75% | 12.2% |
| 35 | CVNA | Carvana CO. | Decreased | $95.8M | 0.75% | 14.6% |
| 36 | SYRE | Spyre Therapeutics, Inc. | Increased | $94.4M | 0.74% | 15.3% |
| 37 | CR | Crane Co | Decreased | $93.3M | 0.73% | 1.4% |
| 38 | VSECU | Vse Corp. | Increased | $89.9M | 0.70% | — |
| 39 | RMBS | Rambus Inc. | Increased | $87.7M | 0.69% | 8.7% |
| 40 | MNMD | Mind Medicine Inc. | Increased | $87.5M | 0.69% | — |
| 41 | TMDXOther Healthcare | TransMedics Group, Inc. | Decreased | $86.6M | 0.68% | 41.5% |
| 42 | PTCT | PTC Therapeutics Inc. | Increased | $86.3M | 0.68% | 12.2% |
| 43 | SPXC | SPX Technologies, Inc. | Increased | $86.0M | 0.67% | 3.0% |
| 44 | ITUB | Itau Unibanco Holding S.A. | Increased | $84.9M | 0.67% | 0.3% |
| 45 | KYMR | Kymera Therapeutics Inc. | Increased | $83.2M | 0.65% | 14.6% |
| 46 | COHR | Coherent Corp. | Increased | $82.7M | 0.65% | 6.9% |
| 47 | MTSI | MACOM Technology Solutions Holdings, Inc. | Increased | $82.6M | 0.65% | 4.5% |
| 48 | CPA | Copa Holdings, S.A. | Increased | $80.9M | 0.63% | 5.7% |
| 49 | IMNM | Immunome Inc. | Increased | $79.6M | 0.62% | 16.3% |
| 50 | AXON | Axon Enterprise, Inc. | Decreased | $77.4M | 0.61% | 3.7% |
| 51 | AVAV | AeroVironment Inc. | Decreased | $77.4M | 0.61% | 10.2% |
| 52 | TRPCF | Trip.com Group Ltd. | Increased | $77.1M | 0.60% | — |
| 53 | RSI | Rush Street Interactive, Inc. | Decreased | $75.6M | 0.59% | 5.9% |
| 54 | VALE | Vale S.A. | Increased | $75.3M | 0.59% | 1.4% |
| 55 | ROAD | Construction Partners, Inc. | Decreased | $75.3M | 0.59% | 5.9% |
| 56 | ARQT | Arcus Biosciences Inc. | Increased | $74.4M | 0.58% | 15.6% |
| 57 | INDV | Indivior Pharmaceuticals, Inc. | Increased | $71.8M | 0.56% | 9.8% |
| 58 | PAY | Paymentus Holdings, Inc. | Decreased | $70.7M | 0.55% | 3.6% |
| 59 | SOJF | Southern CO | Decreased | $69.8M | 0.55% | — |
| 60 | NXT | Nextpower Inc. | Increased | $69.7M | 0.55% | 5.4% |
| 61 | SMTC | Semtech Corp. | Increased | $68.6M | 0.54% | 5.6% |
| 62 | FLS | Flowserve Corp. | Decreased | $67.8M | 0.53% | 4.1% |
| 63 | WULF | Terawulf Inc. | Decreased | $67.4M | 0.53% | 27.8% |
| 64 | GGAL | Grupo Financiero Galicia SA | Increased | $66.7M | 0.52% | 20.7% |
| 65 | LC | LendingClub Corp. | Decreased | $66.7M | 0.52% | 5.9% |
| 66 | HCIIP | HCI Group, Inc. | Decreased | $66.4M | 0.52% | — |
| 67 | MDGL | Madrigal Pharmaceuticals Inc. | Decreased | $65.0M | 0.51% | 19.8% |
| 68 | ULS | UL Solutions Inc. | Increased | $64.5M | 0.51% | 6.4% |
| 69 | MOD | Modine Manufacturing CO | Decreased | $64.1M | 0.50% | 7.9% |
| 70 | BOOT | Boot Barn Holdings, Inc. | Decreased | $63.6M | 0.50% | 12.1% |
| 71 | FTI | TechnipFMC plc | Decreased | $61.7M | 0.48% | 2.7% |
| 72 | PAASF | Pan American Silver Corp. | Decreased | $61.6M | 0.48% | — |
| 73 | ATECOther Healthcare | Alphatec Holdings, Inc. | Increased | $60.1M | 0.47% | 12.2% |
| 74 | OSIS | Osi Systems Inc. | Increased | $60.1M | 0.47% | 16.8% |
| 75 | TNL | Travel & Leisure Co. | Increased | $59.8M | 0.47% | 5.7% |
| 76 | STRL | Sterling Infrastructure, Inc. | Decreased | $59.6M | 0.47% | 7.3% |
| 77 | LEU | Centrus Energy Corp. | Decreased | $59.3M | 0.46% | 22.8% |
| 78 | CUBB | Customers Bancorp, Inc. | Increased | $56.0M | 0.44% | — |
| 79 | CRDO | Credo Technology Group Holding Ltd. | Decreased | $55.2M | 0.43% | 5.7% |
| 80 | ONTO | Onto Innovation Inc. | Increased | $55.1M | 0.43% | 3.4% |
| 81 | GRABW | Grab Holdings Ltd. | Increased | $54.9M | 0.43% | — |
| 82 | IAG | Iamgold Corp. | Increased | $54.0M | 0.42% | — |
| 83 | MIR | Mirion Technologies, Inc. | Increased | $53.8M | 0.42% | 13.9% |
| 84 | IBP | Installed Building Products, Inc. | Decreased | $53.8M | 0.42% | 7.9% |
| 85 | ORA | Ormat Technologies, Inc. | Increased | $52.3M | 0.41% | 8.8% |
| 86 | TPTX | Turning Point Therapeutics Inc. | Increased | $52.2M | 0.41% | — |
| 87 | WGSWWOther Healthcare | GeneDx Holdings Corp. | Decreased | $51.4M | 0.40% | — |
| 88 | ECG | Everus Construction Group, Inc. | Decreased | $50.8M | 0.40% | 3.9% |
| 89 | MYRG | Myr Group Inc. | New | $50.0M | 0.39% | 5.6% |
| 90 | NUVL | Nuvalent Inc. | Increased | $48.6M | 0.38% | 15.2% |
| 91 | BROS | Dutch Bros Inc. | Increased | $48.4M | 0.38% | 58.7% |
| 92 | SAIA | Saia Inc. | Increased | $47.8M | 0.37% | 5.7% |
| 93 | SE | Sea Ltd. | Increased | $47.4M | 0.37% | 6.4% |
| 94 | CLS | Celestica Inc. | Decreased | $47.2M | 0.37% | 2.8% |
| 95 | DY | Dycom Industries Inc. | Decreased | $46.7M | 0.37% | 8.0% |
| 96 | SNEX | StoneX Group Inc. | Increased | $46.0M | 0.36% | 5.1% |
| 97 | ALH | Alliance Laundry Holdings Inc. | New | $44.9M | 0.35% | 14.9% |
| 98 | ADPT | Adaptive Biotechnologies Corporation | Decreased | $44.8M | 0.35% | 7.7% |
| 99 | BE | Bloom Energy Corp. | Decreased | $44.8M | 0.35% | 9.9% |
| 100 | MBX | MBX Biosciences, Inc. | Decreased | $44.4M | 0.35% | 9.7% |
| 101 | ESE | Esco Technologies Inc. | Decreased | $44.0M | 0.35% | 1.9% |
| 102 | THO | Thor Industries Inc. | Decreased | $43.9M | 0.34% | 8.2% |
| 103 | GLOB | Globant S.A. | Increased | $43.5M | 0.34% | 14.8% |
| 104 | JBTM | Jbt Marel Corp. | Decreased | $43.3M | 0.34% | 5.5% |
| 105 | TER | Teradyne, Inc. | Increased | $42.8M | 0.34% | 3.8% |
| 106 | PWR | Quanta Services, Inc. | Decreased | $42.7M | 0.33% | 3.3% |
| 107 | SGI | Somnigroup International Inc. | Increased | $41.1M | 0.32% | 6.0% |
| 108 | CMPSOther Healthcare | COMPASS Pathways plc | Increased | $40.9M | 0.32% | 5.7% |
| 109 | DOO | Brp Inc. | Increased | $40.7M | 0.32% | — |
| 110 | HOOD | Robinhood Markets, Inc. | Increased | $40.4M | 0.32% | 3.9% |
| 111 | AXSM | Axsome Therapeutics Inc. | Decreased | $40.3M | 0.32% | 6.4% |
| 112 | HBM | Hudbay Minerals Inc. | Decreased | $39.3M | 0.31% | — |
| 113 | IMAX | Imax Corp. | Increased | $37.8M | 0.30% | 13.7% |
| 114 | FIX | Comfort Systems Usa Inc. | Decreased | $37.8M | 0.30% | 2.4% |
| 115 | NXE | NexGen Energy Ltd. | Increased | $37.8M | 0.30% | — |
| 116 | AMLX | Amylyx Pharmaceuticals, Inc. | Increased | $37.6M | 0.29% | 13.6% |
| 117 | CAE | Cae Inc. | Decreased | $36.7M | 0.29% | — |
| 118 | ATROB | Astronics Corp. | Increased | $36.2M | 0.28% | — |
| 119 | SHOO | Steven Madden, Ltd. | New | $35.7M | 0.28% | 9.2% |
| 120 | LECO | Lincoln Electric Holdings Inc. | Increased | $35.7M | 0.28% | 1.2% |
| 121 | AEM | Agnico Eagle Mines Ltd. | Decreased | $35.5M | 0.28% | 1.1% |
| 122 | TNDMOther Healthcare | Tandem Diabetes Care Inc. | Increased | $35.4M | 0.28% | 21.3% |
| 123 | VSOGF | Vista Energy, S.A.B. de C.V. | Increased | $35.2M | 0.28% | — |
| 124 | CECO | Ceco Environmental Corp. | Increased | $34.7M | 0.27% | 10.8% |
| 125 | TVTX | Travere Therapeutics Inc. | Increased | $34.4M | 0.27% | 14.6% |
| 126 | GIL | Gildan Activewear Inc. | Increased | $33.7M | 0.26% | 3.4% |
| 127 | LIVNOther Healthcare | LivaNova PLC | Decreased | $33.5M | 0.26% | 5.9% |
| 128 | ASND | Ascendis Pharma A/S | Decreased | $33.3M | 0.26% | 7.5% |
| 129 | TKO | TKO Group Holdings, Inc. | Increased | $33.2M | 0.26% | 12.9% |
| 130 | VSCO | Victoria's Secret & Co. | New | $32.6M | 0.26% | 20.0% |
| 131 | RBC | RBC Bearings Inc. | Decreased | $32.5M | 0.25% | 0.9% |
| 132 | IVVD | Invivyd, Inc. | Increased | $32.3M | 0.25% | 10.5% |
| 133 | GPOR | Gulfport Energy Corp. | Decreased | $32.2M | 0.25% | 4.9% |
| 134 | INSPOther Healthcare | Inspire Medical Systems, Inc. | Increased | $32.1M | 0.25% | 14.6% |
| 135 | AXP | American Express CO | Decreased | $31.7M | 0.25% | 2.3% |
| 136 | TPR | Tapestry, Inc. | Decreased | $30.5M | 0.24% | 6.8% |
| 137 | SITE | SiteOne Landscape Supply, Inc. | Decreased | $30.4M | 0.24% | 5.7% |
| 138 | IESC | IES Holdings, Inc. | Decreased | $30.0M | 0.23% | 12.0% |
| 139 | CAMT | Camtek Ltd. | Increased | $29.9M | 0.23% | 11.8% |
| 140 | SIMO | Silicon Motion Technology Corp. | Decreased | $29.6M | 0.23% | 1.4% |
| 141 | LGN | Legence Corp. | New | $29.5M | 0.23% | 9.3% |
| 142 | EVR | Evercore Inc. | Increased | $29.5M | 0.23% | 1.8% |
| 143 | BBNXOther Healthcare | Beta Bionics, Inc. | Decreased | $29.2M | 0.23% | 17.8% |
| 144 | NEO | Neogenomics Inc. | Increased | $29.1M | 0.23% | 8.9% |
| 145 | ALNY | Alnylam Pharmaceuticals Inc. | Increased | $27.7M | 0.22% | 4.3% |
| 146 | LASR | Nlight, Inc. | New | $27.5M | 0.22% | 4.6% |
| 147 | RCKT | Rocket Pharmaceuticals Inc. | Decreased | $27.4M | 0.22% | 26.2% |
| 148 | ARLO | Arlo Technologies, Inc. | Decreased | $27.3M | 0.21% | 12.2% |
| 149 | VCYT | Veracyte, Inc. | Increased | $26.6M | 0.21% | 7.5% |
| 150 | EVLVW | Evolv Technologies Holdings, Inc. | Decreased | $26.6M | 0.21% | — |
| 151 | AWI | Armstrong World Industries Inc. | Increased | $26.4M | 0.21% | 2.7% |
| 152 | KNSA | Kiniksa Pharmaceuticals International, plc | Decreased | $26.1M | 0.20% | 8.9% |
| 153 | AMBA | Ambarella Inc. | Decreased | $25.9M | 0.20% | 6.1% |
| 154 | APLD | Applied Digital Corp. | Decreased | $25.6M | 0.20% | 30.6% |
| 155 | FIVE | Five Below, Inc. | Decreased | $25.0M | 0.20% | 3.0% |
| 156 | CELC | Celcuity Inc. | Increased | $24.9M | 0.20% | 20.9% |
| 157 | CDE | Coeur Mining, Inc. | Increased | $24.8M | 0.19% | 4.4% |
| 158 | ATI | Ati Inc. | Increased | $24.5M | 0.19% | 4.2% |
| 159 | PRM | Perimeter Solutions, Inc. | New | $23.9M | 0.19% | 3.0% |
| 160 | MIAX | Miami International Holdings, Inc. | Increased | $23.6M | 0.19% | — |
| 161 | AORTOther Healthcare | Artivion, Inc. | Increased | $23.6M | 0.18% | 4.1% |
| 162 | ALM | Almonty Industries Inc. | Decreased | $23.4M | 0.18% | — |
| 163 | XERS | Xeris Biopharma Holdings, Inc. | Increased | $23.4M | 0.18% | 9.8% |
| 164 | NPCEOther Healthcare | NeuroPace Inc. | Increased | $23.3M | 0.18% | 4.7% |
| 165 | FIGS | Figs, Inc. | New | $23.2M | 0.18% | 12.3% |
| 166 | PPTA | Perpetua Resources Corp. | Decreased | $23.2M | 0.18% | 10.7% |
| 167 | LGNZZ | Ligand Pharmaceuticals Inc. | Decreased | $23.1M | 0.18% | — |
| 168 | DQ | Daqo New Energy Corp. | Increased | $23.0M | 0.18% | 6.7% |
| 169 | GHM | Graham Corp. | New | $22.8M | 0.18% | 3.3% |
| 170 | CASY | Caseys General Stores Inc. | Increased | $22.8M | 0.18% | 2.9% |
| 171 | MTZ | Mastec Inc. | Increased | $22.6M | 0.18% | 4.6% |
| 172 | PRCH | Porch Group, Inc. | Decreased | $22.5M | 0.18% | 25.2% |
| 173 | BWXT | BWX Technologies, Inc. | Decreased | $22.5M | 0.18% | 4.1% |
| 174 | ALKS | Alkermes plc | Decreased | $22.3M | 0.17% | 17.9% |
| 175 | MRCY | Mercury Systems Inc. | Increased | $22.2M | 0.17% | 7.8% |
| 176 | WLDN | Willdan Group, Inc. | Increased | $21.8M | 0.17% | 6.9% |
| 177 | PSMT | Pricesmart Inc. | Increased | $21.6M | 0.17% | 9.2% |
| 178 | WWD | Woodward, Inc. | New | $21.4M | 0.17% | 1.1% |
| 179 | DRUG | Bright Minds Biosciences Inc. | Increased | $21.0M | 0.16% | 7.0% |
| 180 | VKTX | Viking Therapeutics Inc. | Increased | $21.0M | 0.16% | 25.1% |
| 181 | ALNT | Allient Inc. | New | $20.8M | 0.16% | 5.9% |
| 182 | NBIX | Neurocrine Biosciences Inc. | Increased | $20.6M | 0.16% | 5.1% |
| 183 | AR | Antero Resources Corp. | Increased | $20.1M | 0.16% | 3.5% |
| 184 | LPTH | Lightpath Technologies Inc. | New | $19.9M | 0.16% | 6.2% |
| 185 | BLD | TopBuild Corp. | Increased | $19.5M | 0.15% | 7.2% |
| 186 | ROKU | Roku, Inc. | Increased | $19.5M | 0.15% | 5.9% |
| 187 | PRLB | Proto Labs Inc. | New | $19.3M | 0.15% | 3.6% |
| 188 | AMD | Advanced Micro Devices Inc. | Increased | $19.2M | 0.15% | 2.0% |
| 189 | UUUU | Energy Fuels Inc. | Decreased | $19.1M | 0.15% | 15.9% |
| 190 | AMPX-WT | Amprius Technologies, Inc. | Decreased | $18.9M | 0.15% | — |
| 191 | INSM | Insmed Incorporated | Increased | $18.4M | 0.14% | 5.2% |
| 192 | NP | Neptune Insurance Holdings Inc. | New | $18.1M | 0.14% | 12.9% |
| 193 | ASTS | AST SpaceMobile, Inc. | Decreased | $17.9M | 0.14% | 20.1% |
| 194 | ANDG | Andersen Group Inc. | New | $17.9M | 0.14% | 26.1% |
| 195 | AGYS | Agilysys Inc. | Decreased | $17.7M | 0.14% | 5.4% |
| 196 | OPLN | Openlane, Inc. | Decreased | $17.5M | 0.14% | 2.4% |
| 197 | QXO-PB | Qxo, Inc. | Increased | $16.4M | 0.13% | — |
| 198 | TCMDOther Healthcare | Tactile Systems Technology Inc. | Increased | $16.4M | 0.13% | 8.5% |
| 199 | DLTR | Dollar Tree, Inc. | New | $16.4M | 0.13% | 7.8% |
| 200 | AFRM | Affirm Holdings, Inc. | Decreased | $16.2M | 0.13% | 5.6% |
| 201 | HLIO | Helios Technologies, Inc. | Increased | $15.8M | 0.12% | 3.8% |
| 202 | MAZE | Maze Therapeutics, Inc. | $15.7M | 0.12% | 8.7% | |
| 203 | LOPE | Grand Canyon Education, Inc. | Decreased | $15.6M | 0.12% | 5.5% |
| 204 | STNE | StoneCo Ltd. | Decreased | $15.4M | 0.12% | 10.2% |
| 205 | GRDNOther Healthcare | Guardian Pharmacy Services, Inc. | Decreased | $15.2M | 0.12% | 11.8% |
| 206 | PGEN | Precigen Inc. | Increased | $15.1M | 0.12% | 17.4% |
| 207 | EXEL | Exelixis Inc. | Increased | $14.8M | 0.12% | 14.2% |
| 208 | AMRC | Ameresco, Inc. | Increased | $14.8M | 0.12% | 12.3% |
| 209 | GMEDOther Healthcare | Globus Medical Inc. | Increased | $14.6M | 0.11% | 2.3% |
| 210 | TATT | Tat Technologies Ltd. | Increased | $14.5M | 0.11% | 2.2% |
| 211 | LCII | Lci Industries | Increased | $14.4M | 0.11% | 14.0% |
| 212 | W | Wayfair Inc. | Increased | $14.4M | 0.11% | 23.3% |
| 213 | CELH | Celsius Holdings, Inc. | Decreased | $14.4M | 0.11% | 13.9% |
| 214 | CPS | Cooper-Standard Holdings Inc. | Increased | $14.4M | 0.11% | 3.8% |
| 215 | ULTA | Ulta Beauty, Inc. | Increased | $14.3M | 0.11% | 5.7% |
| 216 | ARGX | argenx SE | Decreased | $14.2M | 0.11% | 3.4% |
| 217 | FSLY | Fastly, Inc. | Increased | $14.1M | 0.11% | 12.5% |
| 218 | PODDOther Healthcare | Insulet Corp. | Decreased | $14.0M | 0.11% | 5.5% |
| 219 | ALSN | Allison Transmission Holdings Inc. | Increased | $14.0M | 0.11% | 4.2% |
| 220 | DXPE | Dxp Enterprises Inc. | Decreased | $13.9M | 0.11% | 3.8% |
| 221 | TDUP | ThredUp Inc. | Decreased | $13.8M | 0.11% | 20.0% |
| 222 | JBIO | Jade Biosciences, Inc. | Decreased | $13.7M | 0.11% | — |
| 223 | CGNT | Cognyte Software Ltd. | Increased | $13.5M | 0.11% | 0.8% |
| 224 | XZO | Exzeo Group, Inc. | New | $13.3M | 0.10% | 4.4% |
| 225 | IFS | Intercorp Financial Services Inc. | Decreased | $13.2M | 0.10% | 1.1% |
| 226 | PSIX | Power Solutions International, Inc. | Increased | $13.1M | 0.10% | 13.0% |
| 227 | LBRT | Liberty Energy Inc. | Increased | $13.1M | 0.10% | 11.6% |
| 228 | SWIM | Latham Group, Inc. | Decreased | $13.0M | 0.10% | 5.1% |
| 229 | LTH | Life Time Group Holdings, Inc. | Decreased | $13.0M | 0.10% | 6.7% |
| 230 | ABCL | AbCellera Biologics Inc. | Increased | $12.9M | 0.10% | 21.5% |
| 231 | INCY | Incyte Corporation | Increased | $12.7M | 0.10% | 7.8% |
| 232 | LAUR | Laureate Education, Inc. | Decreased | $12.6M | 0.10% | 2.6% |
| 233 | CAHOther Healthcare | Cardinal Health Inc. | Increased | $12.3M | 0.10% | 3.0% |
| 234 | SHLS | Shoals Technologies Group, Inc. | Increased | $11.9M | 0.09% | 11.1% |
| 235 | GENI | Genius Sports Ltd. | Decreased | $11.5M | 0.09% | 6.3% |
| 236 | UCTT | Ultra Clean Holdings, Inc. | Increased | $11.5M | 0.09% | 9.2% |
| 237 | DSGN | Design Therapeutics, Inc. | Increased | $11.1M | 0.09% | 4.6% |
| 238 | WT | WisdomTree, Inc. | Decreased | $10.7M | 0.08% | 27.6% |
| 239 | INOD | Innodata Inc. | Decreased | $10.5M | 0.08% | 15.4% |
| 240 | HUT | Hut 8 Corp. | Decreased | $10.0M | 0.08% | 16.6% |
| 241 | UTI | Universal Technical Institute Inc. | Increased | $9.6M | 0.08% | 7.3% |
| 242 | MAMA | Mama's Creations, Inc. | New | $9.6M | 0.07% | 7.3% |
| 243 | RLMD | Relmada Therapeutics, Inc. | Increased | $9.1M | 0.07% | 5.1% |
| 244 | GWRE | Guidewire Software, Inc. | Decreased | $8.7M | 0.07% | 5.6% |
| 245 | POWL | Powell Industries Inc. | Decreased | $8.6M | 0.07% | 40.8% |
| 246 | VITL | Vital Farms, Inc. | Decreased | $8.2M | 0.06% | 30.6% |
| 247 | LIND | Lindblad Expeditions Holdings, Inc. | Decreased | $8.2M | 0.06% | 11.2% |
| 248 | HLMN | Hillman Solutions Corp. | Decreased | $8.1M | 0.06% | 2.6% |
| 249 | AS | Amer Sports, Inc. | Decreased | $7.7M | 0.06% | 8.3% |
| 250 | ATAT | Atour Lifestyle Holdings Ltd. | Increased | $7.6M | 0.06% | 4.0% |
| 251 | KFIIU | K&F Growth Acquisition Corp. II | Increased | $7.5M | 0.06% | — |
| 252 | TDGMW | Tidewater Inc. | Decreased | $7.5M | 0.06% | — |
| 253 | AGX | Argan Inc. | Decreased | $7.5M | 0.06% | 6.0% |
| 254 | BRCB | Black Rock Coffee Bar, Inc. | Increased | $7.5M | 0.06% | 12.4% |
| 255 | BEAGR | Bold Eagle Acquisition Corp. | Decreased | $7.2M | 0.06% | — |
| 256 | PTRN | Pattern Group Inc. | Decreased | $7.1M | 0.06% | 5.4% |
| 257 | BEIGF | BeOne Medicines Ltd. | Increased | $7.1M | 0.06% | — |
| 258 | PRTO | Protara Therapeutics, Inc. | Increased | $6.7M | 0.05% | — |
| 259 | UTHR | United Therapeutics Corporation | Decreased | $6.5M | 0.05% | 8.6% |
| 260 | CNNE | Cannae Holdings, Inc. | Decreased | $6.5M | 0.05% | 11.8% |
| 261 | WSC | WillScot Holdings Corp. | Decreased | $6.0M | 0.05% | 15.3% |
| 262 | ANIP | Ani Pharmaceuticals Inc. | Decreased | $6.0M | 0.05% | 20.0% |
| 263 | TBBB | Bbb Foods Inc. | Increased | $6.0M | 0.05% | 8.4% |
| 264 | ANRO | Alto Neuroscience, Inc. | New | $6.0M | 0.05% | 7.8% |
| 265 | GDEN | Golden Entertainment, Inc. | $6.0M | 0.05% | 4.0% | |
| 266 | TE-WT | T1 Energy Inc. | New | $5.6M | 0.04% | — |
| 267 | INVLW | Innventure, Inc. | New | $5.3M | 0.04% | — |
| 268 | GXO | GXO Logistics, Inc. | $5.2M | 0.04% | 5.1% | |
| 269 | HVMCW | Highview Merger Corp. | New | $5.0M | 0.04% | — |
| 270 | BLFY | Blue Foundry Bancorp | $5.0M | 0.04% | 3.8% | |
| 271 | GOOG | Alphabet Inc. | Decreased | $4.4M | 0.03% | — |
| 272 | WLACW | Willow Lane Acquisition Corp. | $4.0M | 0.03% | — | |
| 273 | NHICW | NewHold Investment Corp. III | Decreased | $3.8M | 0.03% | — |
| 274 | VINP | Vinci Compass Investments Ltd. | $3.6M | 0.03% | 0.4% | |
| 275 | NVDA | Nvidia Corp. | Decreased | $3.6M | 0.03% | 1.0% |
| 276 | CBIO | Crescent Biopharma, Inc. | $3.6M | 0.03% | 12.0% | |
| 277 | SION | Sionna Therapeutics, Inc. | $3.5M | 0.03% | 13.1% | |
| 278 | PENN | PENN Entertainment, Inc. | Increased | $3.4M | 0.03% | 16.6% |
| 279 | RNA | Avidity Biosciences Inc. | Decreased | $3.3M | 0.03% | — |
| 280 | GSHRW | Gesher Acquisition Corp. II | Decreased | $3.3M | 0.03% | — |
| 281 | DNMXW | Dynamix Corp III | Increased | $3.0M | 0.02% | — |
| 282 | FULC | Fulcrum Therapeutics Inc. | New | $2.8M | 0.02% | 9.9% |
| 283 | AAPL | Apple Inc. | Increased | $2.7M | 0.02% | 0.8% |
| 284 | PTN | Palatin Technologies Inc. | New | $2.6M | 0.02% | 10.2% |
| 285 | APXTW | Apex Treasury Corp. | New | $2.5M | 0.02% | — |
| 286 | CLYM | Climb Bio, Inc. | Increased | $2.4M | 0.02% | 11.1% |
| 287 | MNPR | Monopar Therapeutics | Decreased | $2.2M | 0.02% | 65.8% |
| 288 | PEPG | PepGen Inc. | $2.1M | 0.02% | 6.2% | |
| 289 | LRMR | Larimar Therapeutics, Inc. | $2.0M | 0.02% | 9.7% | |
| 290 | LATAW | Galata Acquisition Corp. II | New | $2.0M | 0.02% | — |
| 291 | MSFT | Microsoft Corp. | Decreased | $1.9M | 0.02% | 1.1% |
| 292 | GDHLF | GDS Holdings Ltd. | Increased | $1.8M | 0.01% | — |
| 293 | ALXO | Alx Oncology Holdings Inc. | Increased | $1.6M | 0.01% | 1.1% |
| 294 | CAEP | Cantor Equity Partners III, Inc. | Increased | $1.5M | 0.01% | — |
| 295 | WMT | Walmart Inc. | New | $1.2M | 0.01% | 0.9% |
| 296 | COF-PN | Capital One Financial Corp. | Increased | $1.2M | 0.01% | — |
| 297 | AVGO | Broadcom Inc. | Increased | $1.1M | 0.01% | 1.1% |
| 298 | TSLA | Tesla, Inc. | Increased | $1.1M | 0.01% | 1.8% |
| 299 | KO | Coca Cola CO | Increased | $1.1M | 0.01% | — |
| 300 | XOM | Exxon Mobil Corp. | Decreased | $1.1M | 0.01% | 1.4% |
| 301 | EQT | EQT Corp. | Decreased | $1.0M | 0.01% | 3.4% |
| 302 | APP | AppLovin Corp. | Decreased | $1.0M | 0.01% | 4.5% |
| 303 | BDCIW | BTC Development Corp. | New | $1.0M | 0.01% | — |
| 304 | SHOP | Shopify Inc. | Decreased | $958K | 0.01% | 1.5% |
| 305 | LIN | Linde Plc | Decreased | $916K | 0.01% | 1.2% |
| 306 | AZN | Astrazeneca Plc | Increased | $899K | 0.01% | 0.1% |
| 307 | LLY | Eli Lilly & Co | Increased | $884K | 0.01% | 1.0% |
| 308 | BA-PA | Boeing CO | Decreased | $827K | 0.01% | — |
| 309 | PLDGP | Prologis, Inc. | Increased | $752K | 0.01% | — |
| 310 | NGNE | Neurogene Inc. | $675K | 0.01% | 31.2% | |
| 311 | TFC-PR | Truist Financial Corp. | Increased | $660K | 0.01% | — |
| 312 | UNP | Union Pacific Corp. | New | $637K | 0.00% | 5.3% |
| 313 | GILD | Gilead Sciences Inc. | Increased | $618K | 0.00% | 1.6% |
| 314 | NET | Cloudflare, Inc. | Increased | $586K | 0.00% | 2.9% |
| 315 | LRCX | Lam Research Corp. | Decreased | $561K | 0.00% | 2.4% |
| 316 | MRK | Merck & Co., Inc. | Increased | $553K | 0.00% | 1.1% |
| 317 | KEYS | Keysight Technologies, Inc. | New | $535K | 0.00% | 1.2% |
| 318 | VEEVOther Healthcare | Veeva Systems Inc. | Increased | $529K | 0.00% | 3.7% |
| 319 | CGNX | Cognex Corp. | New | $507K | 0.00% | 2.7% |
| 320 | INTC | Intel Corp. | New | $505K | 0.00% | 2.3% |
| 321 | TYL | Tyler Technologies Inc. | New | $504K | 0.00% | 5.3% |
| 322 | HCMAW | Hcm Iii Acquisition Corp. | New | $503K | 0.00% | — |
| 323 | DYORU | Insight Digital Partners II | New | $496K | 0.00% | — |
| 324 | SPOT | Spotify Technology S.A. | Decreased | $476K | 0.00% | 4.1% |
| 325 | WELL | Welltower Inc. | Decreased | $468K | 0.00% | 2.8% |
| 326 | ALAB | Astera Labs, Inc. | Decreased | $451K | 0.00% | 10.7% |
| 327 | BSXOther Healthcare | Boston Scientific Corp. | Decreased | $372K | 0.00% | 1.6% |
| 328 | CEG | Constellation Energy Corp. | Decreased | $360K | 0.00% | 2.9% |
| 329 | SPY | Spdr S&P 500 Etf Trust | New | $316K | 0.00% | — |
| 330 | CCXIW | Churchill Capital Corp XI | Increased | $230K | 0.00% | — |
Top Movers This Quarter
Share changes reflect active decisions. Value changes include price moves.
Frequently asked questions
What stocks did Driehaus Capital own in Q4 2025?
Driehaus Capital held 330 biotech stocks in their 13F portfolio in Q4 2025. Their top positions include CRNX, PRAX, GH, XENE, PLNT. The full holdings table is available on BiotechEdge with position sizes, quarter-over-quarter changes, and AI analysis.
How much was Driehaus Capital's portfolio worth in Q4 2025?
Driehaus Capital's tracked biotech portfolio was worth $12.8B across 330 positions, with total assets under management of approximately $28B. Portfolio values are based on 13F filings with the SEC.
What did Driehaus Capital buy in Q4 2025?
Driehaus Capital initiated 36 new positions in Q4 2025, including MYRG, ALH, SHOO, VSCO, LGN and 31 more. They also increased 152 existing positions.
What did Driehaus Capital sell in Q4 2025?
Driehaus Capital fully exited 440 positions in Q4 2025, including ESAB, EVER, XGN, EXLS, LMT and 435 more. They also trimmed 131 existing positions.
Is Driehaus Capital a biotech fund?
Growth-oriented investment firm founded by Richard Driehaus (d. 2021), now led by CEO Steve Weber. Michael Caldwell manages the healthcare/life sciences portfolio, applying growth-at-a-reasonable-price philosophy to biotech with a focus on companies with accelerating revenue growth and approaching commercial inflection points.
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