OrbiMed Advisors CMPS Position
Active13-Fund ConvergenceOrbiMed Advisors held their position in COMPASS Pathways plc (CMPS) in Q4 2025, holding $81.7M worth of shares across 15,219,994 shares.
The position was first reported in Q1 2023 and has been tracked across 12 quarterly 13F filings.
CMPS is a convergence signal: 13 specialist biotech funds hold this stock, suggesting high institutional conviction.
There is an upcoming Phase 3 readout for Psilocybin in 75 days (Jun 30, 2026), making the timing of OrbiMed's position particularly relevant.
About COMPASS Pathways plc
COMPASS Pathways plc operates as a mental health care company primarily in the United Kingdom and the United States. It develops COMP360, a psilocybin therapy that has completed Phase IIb clinical trials for the treatment of treatment-resistant depression; and is in Phase II clinical trials for the treatment of post-traumatic stress disorder. The company was formerly known as COMPASS Rx Limited and changed its name to COMPASS Pathways plc in August 2020. COMPASS Pathways plc was incorporated in 2020 and is headquartered in London, the United Kingdom.
Full company profile →Short Interest
5.7%
1.2 days to cover
OrbiMed Advisors CMPS Position History
| Quarter | Action | Shares | Change | Value |
|---|---|---|---|---|
| Q4 2025 | Held | 15,219,994 | — | $81.7M |
| Q3 2025 | Held | 15,219,994 | — | $53.3M |
| Q2 2025 | Decreased | 15,219,994 | -7,142,856 | $39.6M |
| Q1 2025 | Held | 22,362,850 | — | $42.5M |
| Q4 2024 | Held | 22,362,850 | — | $32.4M |
| Q3 2024 | Held | 22,362,850 | — | $41.1M |
| Q2 2024 | Held | 22,362,850 | — | $22.4M |
| Q1 2024 | Held | 22,362,850 | — | $44.3M |
| Q4 2023 | Held | 22,362,850 | — | $34.9M |
| Q3 2023 | Held | 22,362,850 | — | $44.1M |
| Q2 2023 | Held | 22,362,850 | — | $71.1M |
| Q1 2023 | New | 22,362,850 | +22,362,850 | $73.1M |
Frequently Asked Questions
Does OrbiMed Advisors own CMPS?
Yes. As of Q4 2025, OrbiMed Advisors holds 15,219,994 shares of COMPASS Pathways plc (CMPS) valued at $81.7M. This data comes from their SEC 13F filing.
How many hedge funds own CMPS?
13 specialist biotech hedge funds currently hold CMPS, including Tang Capital Management, Driehaus Capital, RTW Investments and 9 more. When 3 or more specialist funds hold the same stock, BiotechEdge flags it as a convergence signal.
When did OrbiMed Advisors first buy CMPS?
OrbiMed Advisors's position in CMPS was first reported in Q1 2023. 13F filings are reported with a 45-day delay, so the actual purchase may have occurred earlier in the quarter.
Is OrbiMed Advisors's CMPS position increasing or decreasing?
OrbiMed Advisors held their CMPS position unchanged in the most recent quarter.
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