OrbiMed Advisors CRVS Position
Active5-Fund ConvergenceOrbiMed Advisors held their position in Corvus Pharmaceuticals Inc. (CRVS) in Q4 2025, holding $55.2M worth of shares across 7,165,006 shares.
The position was first reported in Q1 2023 and has been tracked across 12 quarterly 13F filings.
CRVS is a convergence signal: 5 specialist biotech funds hold this stock, suggesting high institutional conviction.
There is an upcoming Phase 2 readout for Soquelitinib in 440 days (Jun 30, 2027), making the timing of OrbiMed's position particularly relevant.
Short interest stands at 23.5% of float with 13.4 days to cover, indicating significant bearish positioning against OrbiMed's long thesis.
About Corvus Pharmaceuticals Inc.
Corvus Pharmaceuticals, Inc., a clinical stage biopharmaceutical company, focuses on the development and commercialization of immuno-oncology therapies. Its lead product candidate is Mupadolimab (CPI-006), an anti-CD73 monoclonal antibody, which is in Phase Ib/II clinical trial for non-small cell lung cancer and head and neck cancers. The company also develops CPI-818, a covalent inhibitor of ITK, which is in Phase I/Ib clinical trial to treat patients with various malignant T-cell lymphomas, as well as designed to inhibit the proliferation of certain malignant T-cells; and Ciforadenant (CPI-444), an oral, small molecule antagonist of the A2A receptor that is in Phase II clinical trial for patients with either advanced or refractory renal cell cancer. Its preclinical stage products include CPI-182, an antibody designed to block inflammation and myeloid suppression; and CPI-935, an adenosine A2B receptor antagonist to prevent fibrosis. Corvus Pharmaceuticals, Inc. has a strategic collaboration with Angel Pharmaceuticals for the development its pipeline of targeted investigational medicines. The company was incorporated in 2014 and is based in Burlingame, California.
Full company profile →Short Interest
23.5%
13.4 days to cover
OrbiMed Advisors CRVS Position History
| Quarter | Action | Shares | Change | Value |
|---|---|---|---|---|
| Q4 2025 | Held | 7,165,006 | — | $55.2M |
| Q3 2025 | Held | 7,165,006 | — | $52.8M |
| Q2 2025 | Increased | 7,165,006 | +221,352 | $28.7M |
| Q1 2025 | Held | 6,943,654 | — | $22.1M |
| Q4 2024 | Held | 6,943,654 | — | $37.1M |
| Q3 2024 | Held | 6,943,654 | — | $36.7M |
| Q2 2024 | Held | 6,943,654 | — | $12.6M |
| Q1 2024 | Held | 6,943,654 | — | $12.4M |
| Q4 2023 | Held | 6,943,654 | — | $12.2M |
| Q3 2023 | Held | 6,943,654 | — | $10.1M |
| Q2 2023 | Held | 6,943,654 | — | $15.9M |
| Q1 2023 | New | 6,943,654 | +6,943,654 | $6.3M |
Frequently Asked Questions
Does OrbiMed Advisors own CRVS?
Yes. As of Q4 2025, OrbiMed Advisors holds 7,165,006 shares of Corvus Pharmaceuticals Inc. (CRVS) valued at $55.2M. This data comes from their SEC 13F filing.
How many hedge funds own CRVS?
5 specialist biotech hedge funds currently hold CRVS, including RTW Investments, Perceptive Advisors, Deerfield Management and 1 more. When 3 or more specialist funds hold the same stock, BiotechEdge flags it as a convergence signal.
When did OrbiMed Advisors first buy CRVS?
OrbiMed Advisors's position in CRVS was first reported in Q1 2023. 13F filings are reported with a 45-day delay, so the actual purchase may have occurred earlier in the quarter.
Is OrbiMed Advisors's CRVS position increasing or decreasing?
OrbiMed Advisors held their CRVS position unchanged in the most recent quarter.
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