OrbiMed Advisors KROS Position
Active5-Fund ConvergenceOrbiMed Advisors trimmed their position in Keros Therapeutics Inc. (KROS) in Q4 2025, holding $16.4M worth of shares across 804,212 shares.
The position was first reported in Q1 2023 and has been tracked across 12 quarterly 13F filings.
KROS is a convergence signal: 5 specialist biotech funds hold this stock, suggesting high institutional conviction.
Short interest stands at 39.6% of float with 4.5 days to cover, indicating significant bearish positioning against OrbiMed's long thesis.
About Keros Therapeutics Inc.
Keros Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of novel treatments for patients suffering from hematological and musculoskeletal disorders with high unmet medical need. The company's lead protein therapeutic product candidate is KER-050, which is being developed for the treatment of low blood cell counts, or cytopenias, including anemia and thrombocytopenia in patients with myelodysplastic syndromes, and in patients with myelofibrosis. It is also developing small molecule product candidate KER-047 that is being developed for the treatment of anemia, and is currently in Phase 1 clinical trial; and KER-012, which is in Phase 1 clinical trial to treat disorders associated with bone loss, such as osteoporosis and osteogenesis imperfecta, and for the treatment of pulmonary arterial hypertension. The company was incorporated in 2015 and is headquartered in Lexington, Massachusetts.
Full company profile →Short Interest
39.6%
4.5 days to cover
OrbiMed Advisors KROS Position History
| Quarter | Action | Shares | Change | Value |
|---|---|---|---|---|
| Q4 2025 | Decreased | 804,212 | -214,522 | $16.4M |
| Q3 2025 | Held | 1,018,734 | — | $16.1M |
| Q2 2025 | Held | 1,018,734 | — | $13.6M |
| Q1 2025 | Held | 1,018,734 | — | $10.4M |
| Q4 2024 | Held | 1,018,734 | — | $16.1M |
| Q3 2024 | Decreased | 1,018,734 | -250,000 | $59.2M |
| Q2 2024 | Held | 1,268,734 | — | $58.0M |
| Q1 2024 | Held | 1,268,734 | — | $84.0M |
| Q4 2023 | Decreased | 1,268,734 | -246,000 | $50.4M |
| Q3 2023 | Held | 1,514,734 | — | $48.3M |
| Q2 2023 | Decreased | 1,514,734 | -164,683 | $60.9M |
| Q1 2023 | New | 1,679,417 | +1,679,417 | $71.7M |
Frequently Asked Questions
Does OrbiMed Advisors own KROS?
Yes. As of Q4 2025, OrbiMed Advisors holds 804,212 shares of Keros Therapeutics Inc. (KROS) valued at $16.4M. This data comes from their SEC 13F filing.
How many hedge funds own KROS?
5 specialist biotech hedge funds currently hold KROS, including Eventide Asset Management, Redmile Group, Tang Capital Management and 1 more. When 3 or more specialist funds hold the same stock, BiotechEdge flags it as a convergence signal.
When did OrbiMed Advisors first buy KROS?
OrbiMed Advisors's position in KROS was first reported in Q1 2023. 13F filings are reported with a 45-day delay, so the actual purchase may have occurred earlier in the quarter.
Is OrbiMed Advisors's KROS position increasing or decreasing?
OrbiMed Advisors trimmed their KROS position in the most recent quarter, reducing by 214,522 shares.
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