OrbiMed Advisors NPCE Position
Active3-Fund ConvergenceOrbiMed Advisors trimmed their position in NeuroPace Inc (NPCE) in Q4 2025, holding $37.2M worth of shares across 2,406,335 shares.
The position was first reported in Q1 2023 and has been tracked across 12 quarterly 13F filings.
NPCE is a convergence signal: 3 specialist biotech funds hold this stock, suggesting high institutional conviction.
There is an upcoming Phase 2 readout in 45 days (May 31, 2026), making the timing of OrbiMed's position particularly relevant.
About NeuroPace Inc
NeuroPace, Inc. operates as a medical device company in the United States. It develops and sells RNS system, a brain-responsive neuromodulation system for treating medically refractory focal epilepsy by delivering personalized real-time treatment at the seizure source. The company's RNS system also records continuous brain activity data; and enables clinicians to monitor patients in person and remotely. It sells its products to hospital facilities for initial RNS system implant procedures and for replacement procedures. The company was incorporated in 1997 and is headquartered in Mountain View, California.
Full company profile →Short Interest
4.7%
4.2 days to cover
OrbiMed Advisors NPCE Position History
| Quarter | Action | Shares | Change | Value |
|---|---|---|---|---|
| Q4 2025 | Decreased | 2,406,335 | -207,849 | $37.2M |
| Q3 2025 | Held | 2,614,184 | — | $27.0M |
| Q2 2025 | Decreased | 2,614,184 | -792,151 | $29.1M |
| Q1 2025 | Held | 3,406,335 | — | $41.9M |
| Q4 2024 | Held | 3,406,335 | — | $38.1M |
| Q3 2024 | Held | 3,406,335 | — | $23.7M |
| Q2 2024 | Decreased | 3,406,335 | -597,632 | $25.8M |
| Q1 2024 | Held | 4,003,967 | — | $52.9M |
| Q4 2023 | Decreased | 4,003,967 | -8,314 | $41.3M |
| Q3 2023 | Held | 4,012,281 | — | $39.0M |
| Q2 2023 | Held | 4,012,281 | — | $18.0M |
| Q1 2023 | New | 4,012,281 | +4,012,281 | $18.6M |
Frequently Asked Questions
Does OrbiMed Advisors own NPCE?
Yes. As of Q4 2025, OrbiMed Advisors holds 2,406,335 shares of NeuroPace Inc (NPCE) valued at $37.2M. This data comes from their SEC 13F filing.
How many hedge funds own NPCE?
3 specialist biotech hedge funds currently hold NPCE, including Driehaus Capital, Deerfield Management. When 3 or more specialist funds hold the same stock, BiotechEdge flags it as a convergence signal.
When did OrbiMed Advisors first buy NPCE?
OrbiMed Advisors's position in NPCE was first reported in Q1 2023. 13F filings are reported with a 45-day delay, so the actual purchase may have occurred earlier in the quarter.
Is OrbiMed Advisors's NPCE position increasing or decreasing?
OrbiMed Advisors trimmed their NPCE position in the most recent quarter, reducing by 207,849 shares.
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