OrbiMed Advisors URGN Position
Active5-Fund ConvergenceOrbiMed Advisors increased their position in UroGen Pharma Ltd. (URGN) in Q4 2025, holding $20.5M worth of shares across 875,487 shares.
The position was first reported in Q2 2025 and has been tracked across 3 quarterly 13F filings.
URGN is a convergence signal: 5 specialist biotech funds hold this stock, suggesting high institutional conviction.
There is an upcoming Phase 3 readout for UGN-104 in 198 days (Oct 31, 2026), making the timing of OrbiMed's position particularly relevant.
Short interest stands at 18.0% of float with 9.1 days to cover, indicating significant bearish positioning against OrbiMed's long thesis.
About UroGen Pharma Ltd.
UroGen Pharma Ltd., a biotechnology company, engages in the development and commercialization novel solutions for specialty cancers and urothelial diseases. It offers RTGel, a polymeric biocompatible and reverse thermal gelation hydrogel to improve therapeutic profiles of existing drugs; and Jelmyto for pyelocalyceal solution. The company's lead product candidate is UGN-102, which is in Phase III clinical trials for the treatment of several forms of non-muscle invasive urothelial cancer that include low-grade upper tract urothelial carcinoma and low-grade non-muscle invasive bladder cancer. It is also developing UGN-301 for the treatment of high-grade non-muscle invasive bladder cancer. The company has a license agreement with Allergan Pharmaceuticals International Limited for developing and commercializing pharmaceutical products that contain RTGel and clostridial toxins; Agenus Inc. to develop, make, use, sell, import, and commercialize products of Agenus for the treatment of cancers of the urinary tract via intravesical delivery; and strategic research collaboration with MD Anderson to advance investigational treatment for high-grade bladder cancer. UroGen Pharma Ltd. was incorporated in 2004 and is based in Princeton, New Jersey.
Full company profile →Short Interest
18.0%
9.1 days to cover
OrbiMed Advisors URGN Position History
Frequently Asked Questions
Does OrbiMed Advisors own URGN?
Yes. As of Q4 2025, OrbiMed Advisors holds 875,487 shares of UroGen Pharma Ltd. (URGN) valued at $20.5M. This data comes from their SEC 13F filing.
How many hedge funds own URGN?
5 specialist biotech hedge funds currently hold URGN, including RTW Investments, RA Capital Management, Cormorant Asset Management and 1 more. When 3 or more specialist funds hold the same stock, BiotechEdge flags it as a convergence signal.
When did OrbiMed Advisors first buy URGN?
OrbiMed Advisors's position in URGN was first reported in Q2 2025. 13F filings are reported with a 45-day delay, so the actual purchase may have occurred earlier in the quarter.
Is OrbiMed Advisors's URGN position increasing or decreasing?
OrbiMed Advisors increased their URGN position in the most recent quarter, adding 186,487 shares.
Get the weekly biotech signal briefing
Fund moves, convergence shifts, insider buys, and catalyst alerts — delivered free every Monday.
URGNCompany Page →
All fund holders, insider trades, catalysts, and cash runway
OrbiMed AdvisorsPortfolio →
Full 13F holdings, sector breakdown, and top movers
Drill into any signal
Fund Convergence
See which stocks multiple specialist funds are buying at once
Catalyst Calendar
Every PDUFA date, Phase 3 readout, and AdCom in one view
Insider Trading
When executives buy their own stock — the strongest bullish signal
Cash Runway
Which biotechs are running low on cash and face dilution risk
Short Squeeze
High short interest + fund buying + upcoming catalyst = squeeze setup
Signal Rankings
Every signal in one composite score — ranked by conviction
Biotech Movers
Stocks with the most signal activity right now across all signals
13F Changes
What top biotech funds bought and sold in the latest 13F filing
Want AI context on every signal? Start free trial →