RTW Investments RGEN Position
Active5-Fund ConvergenceRTW Investments initiated a new position in Repligen Corporation (RGEN) in Q4 2025, holding $174.3M worth of shares across 1,064,000 shares.
RGEN is a convergence signal: 5 specialist biotech funds hold this stock, suggesting high institutional conviction.
Short interest stands at 10.4% of float with 4.9 days to cover, indicating significant bearish positioning against RTW Investments's long thesis.
About Repligen Corporation
Repligen Corporation develops and commercializes bioprocessing technologies and systems for use in biological drug manufacturing process in North America, Europe, the Asia Pacific, and internationally. It offers Protein A ligands that are the binding components of Protein A affinity chromatography resins; and cell culture growth factor products. The company's chromatography products include OPUS pre-packed chromatography columns, which are used in the purification of biologics; and OPUS smaller-scale columns that are used in the high throughput process development screening, viral clearance validation studies, and scale down validation of chromatography processes. It also offers ELISA test kits; and chromatography resins under the CaptivA brand. In addition, the company provides filtration products, such as XCell Alternating Tangential Flow systems that are filtration devices used in upstream perfusion and cell culture processing; TangenX flat sheet cassettes, which are used in downstream biologic drug concentration and formulation processes; KrosFlo tangential flow filtration and tangential flow depth filtration systems; Spectra/Por laboratory and process dialysis products, and SpectraFlo dynamic dialysis systems; and ProConnex single-use hollow fiber. Further, it provides process analytics products, such as slope spectroscopy systems under the SoloVPE, FlowVPE, and FlowVPX brands. The company sells its products to life sciences, biopharmaceutical, and diagnostics companies; laboratory researchers; and contract manufacturing organizations. Repligen Corporation has collaboration agreements with Navigo Proteins GmbH to develop multiple affinity ligands. Repligen Corporation was incorporated in 1981 and is headquartered in Waltham, Massachusetts.
Full company profile →Short Interest
10.4%
4.9 days to cover
Frequently Asked Questions
Does RTW Investments own RGEN?
Yes. As of Q4 2025, RTW Investments holds 1,064,000 shares of Repligen Corporation (RGEN) valued at $174.3M. This data comes from their SEC 13F filing.
How many hedge funds own RGEN?
5 specialist biotech hedge funds currently hold RGEN, including Perceptive Advisors, Driehaus Capital, Eventide Asset Management and 1 more. When 3 or more specialist funds hold the same stock, BiotechEdge flags it as a convergence signal.
When did RTW Investments first buy RGEN?
RTW Investments's position in RGEN was first reported in Q4 2025. 13F filings are reported with a 45-day delay, so the actual purchase may have occurred earlier in the quarter.
Is RTW Investments's RGEN position increasing or decreasing?
RTW Investments initiated a new position in RGEN in the most recent quarter. This is their first reported holding.
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