RTW Investments MIST Position
Active3-Fund ConvergenceRTW Investments held their position in Milestone Pharmaceuticals Inc. (MIST) in Q4 2025, holding $5.1M worth of shares across 2,506,102 shares.
The position was first reported in Q1 2023 and has been tracked across 12 quarterly 13F filings.
MIST is a convergence signal: 3 specialist biotech funds hold this stock, suggesting high institutional conviction.
There is an upcoming Phase 3 readout for Etripamil NS 70 mg in 14 days (Apr 30, 2026), making the timing of RTW Investments's position particularly relevant.
About Milestone Pharmaceuticals Inc.
Milestone Pharmaceuticals Inc., a biopharmaceutical company, focuses on the development and commercialization of cardiovascular medicines. The company is developing etripamil, a novel channel blocker, which is in Phase III clinical trial for the treatment of paroxysmal supraventricular tachycardia in the United States and Canada; and Phase II clinical trial for the treatment of atrial fibrillation and rapid ventricular rate. It has a license and collaboration agreement with Ji Xing Pharmaceuticals to develop and commercialize etripamil prophylactic and therapeutic uses in humans. The company was incorporated in 2003 and is headquartered in Montréal, Canada.
Full company profile →Short Interest
8.2%
6.4 days to cover
RTW Investments MIST Position History
| Quarter | Action | Shares | Change | Value |
|---|---|---|---|---|
| Q4 2025 | Held | 2,506,102 | — | $5.1M |
| Q3 2025 | Held | 2,506,102 | — | $5.0M |
| Q2 2025 | Held | 2,506,102 | — | $4.9M |
| Q1 2025 | Held | 2,506,102 | — | $2.0M |
| Q4 2024 | Decreased | 2,506,102 | -750,000 | $5.9M |
| Q3 2024 | Held | 3,256,102 | — | $4.9M |
| Q2 2024 | Held | 3,256,102 | — | $4.3M |
| Q1 2024 | Held | 3,256,102 | — | $5.8M |
| Q4 2023 | Held | 3,256,102 | — | $5.4M |
| Q3 2023 | Held | 3,256,102 | — | $10.1M |
| Q2 2023 | Held | 3,256,102 | — | $9.3M |
| Q1 2023 | New | 3,256,102 | +3,256,102 | $12.8M |
Frequently Asked Questions
Does RTW Investments own MIST?
Yes. As of Q4 2025, RTW Investments holds 2,506,102 shares of Milestone Pharmaceuticals Inc. (MIST) valued at $5.1M. This data comes from their SEC 13F filing.
How many hedge funds own MIST?
3 specialist biotech hedge funds currently hold MIST, including Boxer Capital, OrbiMed Advisors. When 3 or more specialist funds hold the same stock, BiotechEdge flags it as a convergence signal.
When did RTW Investments first buy MIST?
RTW Investments's position in MIST was first reported in Q1 2023. 13F filings are reported with a 45-day delay, so the actual purchase may have occurred earlier in the quarter.
Is RTW Investments's MIST position increasing or decreasing?
RTW Investments held their MIST position unchanged in the most recent quarter.
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