RTW Investments NGNE Position
Active12-Fund ConvergenceRTW Investments held their position in Neurogene Inc. (NGNE) in Q4 2025, holding $28.1M worth of shares across 1,362,456 shares.
The position was first reported in Q1 2024 and has been tracked across 8 quarterly 13F filings.
NGNE is a convergence signal: 12 specialist biotech funds hold this stock, suggesting high institutional conviction.
There is an upcoming Phase 2 readout in 959 days (Nov 30, 2028), making the timing of RTW Investments's position particularly relevant.
Short interest stands at 31.2% of float with 18.9 days to cover, indicating significant bearish positioning against RTW Investments's long thesis.
About Neurogene Inc.
Neurogene Inc. develops life-changing genetic medicines for patients and their families affected by neurological diseases. Its product candidate includes NGN-401, an investigational AAV9 gene therapy for the treatment of Rett syndrome; and NGN-101 to treat neuronal ceroid lipofuscinosis subtype 5 batten disease. The company is headquartered in New York, New York.
Full company profile →Short Interest
31.2%
18.9 days to cover
RTW Investments NGNE Position History
| Quarter | Action | Shares | Change | Value |
|---|---|---|---|---|
| Q4 2025 | Held | 1,362,456 | — | $28.1M |
| Q3 2025 | Held | 1,362,456 | — | $23.6M |
| Q2 2025 | Increased | 1,362,456 | +13,800 | $20.4M |
| Q1 2025 | Decreased | 1,348,656 | -1,600 | $15.8M |
| Q4 2024 | Increased | 1,350,256 | +215,000 | $30.9M |
| Q3 2024 | Increased | 1,135,256 | +64,691 | $47.6M |
| Q2 2024 | Increased | 1,070,565 | +301,443 | $39.0M |
| Q1 2024 | New | 769,122 | +769,122 | $39.1M |
Frequently Asked Questions
Does RTW Investments own NGNE?
Yes. As of Q4 2025, RTW Investments holds 1,362,456 shares of Neurogene Inc. (NGNE) valued at $28.1M. This data comes from their SEC 13F filing.
How many hedge funds own NGNE?
12 specialist biotech hedge funds currently hold NGNE, including EcoR1 Capital, Redmile Group, Casdin Capital and 8 more. When 3 or more specialist funds hold the same stock, BiotechEdge flags it as a convergence signal.
When did RTW Investments first buy NGNE?
RTW Investments's position in NGNE was first reported in Q1 2024. 13F filings are reported with a 45-day delay, so the actual purchase may have occurred earlier in the quarter.
Is RTW Investments's NGNE position increasing or decreasing?
RTW Investments held their NGNE position unchanged in the most recent quarter.
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