RTW Investments ORKA Position
Active8-Fund ConvergenceRTW Investments increased their position in Oruka Therapeutics, Inc. (ORKA) in Q4 2025, holding $62.4M worth of shares across 2,058,148 shares.
The position was first reported in Q3 2024 and has been tracked across 6 quarterly 13F filings.
ORKA is a convergence signal: 8 specialist biotech funds hold this stock, suggesting high institutional conviction.
There is an upcoming Phase 2 readout for ORKA-001 Induction Dose in 14 days (Apr 30, 2026), making the timing of RTW Investments's position particularly relevant.
Short interest stands at 10.3% of float with 9.1 days to cover, indicating significant bearish positioning against RTW Investments's long thesis.
About Oruka Therapeutics, Inc.
Oruka Therapeutics, Inc. is a biotechnology company, which focuses on developing novel monoclonal antibody therapeutics for PsO and other I&I indications. Its pipeline includes ORKA-001 and ORKA-002. The company is headquartered in Menlo Park, CA.
Full company profile →Short Interest
10.3%
9.1 days to cover
RTW Investments ORKA Position History
Frequently Asked Questions
Does RTW Investments own ORKA?
Yes. As of Q4 2025, RTW Investments holds 2,058,148 shares of Oruka Therapeutics, Inc. (ORKA) valued at $62.4M. This data comes from their SEC 13F filing.
How many hedge funds own ORKA?
8 specialist biotech hedge funds currently hold ORKA, including Deep Track Capital, Commodore Capital, Perceptive Advisors and 4 more. When 3 or more specialist funds hold the same stock, BiotechEdge flags it as a convergence signal.
When did RTW Investments first buy ORKA?
RTW Investments's position in ORKA was first reported in Q3 2024. 13F filings are reported with a 45-day delay, so the actual purchase may have occurred earlier in the quarter.
Is RTW Investments's ORKA position increasing or decreasing?
RTW Investments increased their ORKA position in the most recent quarter, adding 112,499 shares.
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